A Diagnostic Challenge: Pelvic Castleman’s Disease
Keywords:
Castleman's disease, Pelvis, Surgery, Tumor.Abstract
Background: A rare lymph node hyperplasia that resembles malignant tumors is unicentric Castleman's disease. Although, it may appear in any lymph-node basin, the pelvis is an uncommon site for this disease, leading to a challenging preoperative diagnosis.
Case Report: A pelvic tumor was discovered during the infertility sort out of a 31-year-old female. Computed tomography scans showed a pelvic mass with prominent vascular-supply, centrally calcified compressing the urinary bladder. With a malignant pelvic neoplasm diagnosis, a laparotomy was scheduled. At surgery, an 11-cm tumor infiltrating right mayor rectus-abdominis muscle, ipsilateral fallopian tube, and a urinary bladder segment was resected en-bloc. The final histopathology diagnosis was a hyaline-vascular, unicentric Castleman´s disease. After seven years of follow-up, the patient is disease-free.
Conclusion: Unicentric pelvic Castleman's disease resembles malignant tumors and surgery is mandatory for its treatment and diagnosis.
References
Kiguchi H, Ishii T, Ishikawa Y, Masuda S, Asuwa N, Yamafuji K, et al. Castleman's disease of the abdomen and pelvis: report of three cases and a review of the literature. J Gastroenterol 1995; 30(5): 661-6. http://dx.doi.org/10.1007/BF02367795
Bonekamp D, Horton KM, Hruban RH, Fishman EK. Castleman disease: the great mimic. Radiographics 2011; 31(6): 1793-807. http://dx.doi.org/10.1148/rg.316115502
Dispenzieri A, Gertz MA. Treatment of Castleman's disease. Curr Treat Options Oncol 2005; 6(3): 255-66. http://dx.doi.org/10.1007/s11864-005-0008-z
Saeed-Abdul-Rahman I, Al-Amri AM. Castleman disease. Korean J Hematol 2012; 47(3): 163-77. http://dx.doi.org/10.5045/kjh.2012.47.3.163
Talat N, Belgaumkar AP, Schulte KM. Surgery in Castleman's disease: a systematic review of 404 published cases. Ann Surg 2012; 255(4): 677-84. http://dx.doi.org/10.1097/SLA.0b013e318249dcdc
Chen XF, Han H, Li YH, Zhang Y, Qin ZK, Liu ZW, et al. Local Castleman's disease: a report of 17 cases with literature review. Ai Zheng 2008; 27(3): 315-8.
Fields S, Bar-ziv J, Portnoy O, Sasson T, Sherman Y, Libson E. Radiologic spectrum of localized Castleman's disease. Isr J Med Sci 1995; 31: 660-669.
Meador TL, McLarney JK. CT features of Castleman disease of the abdomen and pelvis. AJR Am J Roentgenol 2000; 175(1): 115-8. http://dx.doi.org/10.2214/ajr.175.1.1750115
Xiao L, Zhang ZL, Liu YB, Liu ZY, Li JL, Yu YX, et al. CT and MRI features of Castleman's disease of the abdomen and pelvis. Nan Fang Yi Ke Da Xue Xue Bao 2011; 31(1): 129- 32.
Annunziata G, Martino P, Palazzo S, Vasti MP, Ditonno P, Lucarelli G, et al. US with contrast medium in the diagnosis of abdominal Castleman's disease. Arch Ital Urol Androl 2005; 77(1): 76-8.
Zhou LP, Zhang B, Peng WJ, Yang WT, Guan YB, Zhou KR. Imaging findings of Castleman disease of the abdomen and pelvis. Abdom Imaging 2008; 33(4): 482-8. http://dx.doi.org/10.1007/s00261-007-9282-5
Murphy SP, Nathan MA, Karwal MW. FDG-PET appearance of pelvic Castleman's disease. J Nucl Med 1997; 38(8): 1211-2. Murphy
Chang SD, Thoeni RF. Castleman's disease presenting as an adnexal mass: ultrasound, CT and MRI features. Br J Radiol 2004; 77(914): 161-3. http://dx.doi.org/10.1259/bjr/30098414
Song JJ, Jung MH, Woo JS, Chae SW, Hwang SJ, Lee HM. Castleman's disease of the head and neck. Eur Arch Otorhinolaryngol 2006; 263(2): 160-3. http://dx.doi.org/10.1007/s00405-005-0963-9
Nanda A, Handa U, Punia RS, Mohan H. Fine needle aspiration in retroperitoneal Castleman's disease: a case report. Acta Cytol 2009; 53(3): 316-8. http://dx.doi.org/10.1159/000325316
Somdas MA, Ketenci I, Bicer S, Senturk M, Guney E. Castleman's disease as an unusual neck mass: case report. Ann Otol Rhinol Laryngol 2004; 113(6): 459-61.
Beraldo S, Altavilla G, Bernante P, Pelizzo MR. Castleman's disease as an uncommon cause of a neck mass. Acta Otolaryngol 2006; 126(1): 108-11. http://dx.doi.org/10.1080/00016480510012255
Von Schwarzenberg H, Wacker HH, Elfeldt RJ, Brinkmann G, Heller M. Morbus Castleman: Auswertung von 338 Fällen. Fortschr Röntgenstr 1995; 163: 474-79. http://dx.doi.org/10.1055/s-2007-1016032
Sobrevilla-Calvo PJ, Avilés-Salas A, Cortés-Padilla DE, Rivas-Vera S. Clinical and pathological features of Castleman's disease: experience at the Instituto Nacional de Cancerología, Mexico City. Cir Cir 2009; 77(3): 187-92.
Takeda A, Oguchi K, Doi T, Kato H.
[Castleman disease in the pelvic retroperitoneum] Hinyokika Kiyo 1990; 36(9): 1093-6.
MacDonald SR, Lurain JR, Hoff F, Variakojis D, Fishman DA. Castleman disease presenting as a pelvic mass. Obstet Gynecol 1996; 87(5 Pt 2): 875-7.
Florez J, Garcia-Pardo G, Auguet T, Sirvent JJ, Bel M, Richart C. Pelvic mass in 46-year old man. Postgrad Med J 1997; 73(860): 371-3. http://dx.doi.org/10.1136/pgmj.73.860.371
Watson GM, Keane A, Chawdhery Z. Pelvic Castleman's disease shown by angiography and MRI. Eur Radiol 2000; 10(11): 1837. http://dx.doi.org/10.1007/s003300000505
Cammisuli E, Catania V, Santuccio A, Pennisi S. Castleman's disease: a case report. Ann Ital Chir 2003; 74(6): 713-6.
Hsieh CH, Changchien CC, Lan KC, Huang CC, Shen CC, Chang SY, et al. Pelvic Castleman's disease presenting as an adnexal tumor. Acta Obstet Gynecol Scand 2004; 83(3): 311-3.
Nakamura Y, Tokuyama O, Muso A, Kawamura N, Yasui T, Ishiko O. Asymptomatic pelvic Castleman disease in an infertile woman: case report. Arch Gynecol Obstet 2004; 269(2): 156-8. http://dx.doi.org/10.1007/s00404-002-0420-6
Kakuta Y, Takaha N, Nishimura K, Nonomura N, Okuyama A. Castleman disease in the pelvic cavity Hinyokika Kiyo 2005; 51(1): 49-52.
Kawamura N, Hayashi T, Abe T, Nakayama J, Mori N, Sekii K, et al. Castleman's disease in the pelvic cavity. Hinyokika Kiyo 2007; 53(2): 141-4.
Zhou LP, Zhang B, Peng WJ, Yang WT, Guan YB, Zhou KR. Imaging findings of Castleman disease of the abdomen and pelvis. Abdom Imaging 2008; 33(4): 482-8. http://dx.doi.org/10.1007/s00261-007-9282-5
Hwang MR, Chang HJ, Kim MJ, Seo GJ, Yoo SB, Park JW, et al. Castleman's disease of the mesorectum: report of a case. Surg Today 2011; 41(2): 271-5. http://dx.doi.org/10.1007/s00595-009-4206-3
Cascales PA, Gil J, Fuster M, Lloret F, Parrilla P. Castleman's disease of the pelvis. Cir Esp 2012; 90(7): 466- 7. http://dx.doi.org/10.1016/j.ciresp.2011.04.017
Sato A. Castleman's disease in the pelvic retroperitoneum: A case report and review of the Japanese literature. Int J Surg Case Rep 2013; 4(1): 19-22. http://dx.doi.org/10.1016/j.ijscr.2012.08.016
Shi BB, Li HZ, Rong S, Zhao YJ, Fan H. Surgical diagnosis and treatment of Castleman's disease. Zhonghua Yi Xue Za Zhi 2006; 86(3): 174-5.
Dong Y, Na J, Lv J, Wang R, Chen X, Li N, et al. Clinical and laboratory characterization of a large cohort of patients with Castleman disease retrospectively collected from a single center. Leuk Lymphoma 2009; 50(8): 1308-17. http://dx.doi.org/10.1080/10428190903060095