Pleuropericarditis and Exudative Pleural and Pericardial Effusions after Administration of Shingrix Vaccine
Abstract
The adjuvanted subunit vaccine, Shingrix (GSK, Belgium) is now preferred over the live attenuated virus vaccine Zostavax (MSD, USA) due to its comparatively longer immune response durability. Autoimmune/autoinflammatory Syndrome Induced by Adjuvants (ASIA) refers to immune mediated disease triggered by adjuvants in vaccines intended to enhance antigen-specific immune response. Clinicians should be aware of this syndrome given the replacement of Zostavax by Shingrix. We present the first reported case of pleuropericarditis associated with Shingrix vaccine.
References
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